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Efficient Hybrid Synthesis of Amycretin

Multi-receptor agonist peptides represent one of the fastest-growing frontiers in metabolic disease therapeutics. Molecules such as amycretin, a dual GLP-1 and amylin receptor agonist, combine two...

API Substance Quality as a Determinant of Formulation Outcomes: A Review of Sodium Caprate-Enhanced Oral Semaglutide Tablet Development

Oral delivery of semaglutide is limited by low membrane permeability and gastrointestinal degradation, restricting unassisted bioavailability to well below one percent, a barrier Rybelsus® overcomes...

Reagent-Quenching for Reducing Solvent Consumption in Solid-Phase Peptide Synthesis

This paper describes a reagent-quenching strategy in which a Brønsted acid compound is introduced during the post-deprotection wash to chemically neutralize residual piperidine in situ, converting it...

Exhibition at CPHI China 2026

Reflecting on a strong showing at CPHI China, with gratitude to the entire Sinopep team whose collective effort makes moments like this possible...

TIDES 2026 Sinopep Exhibition in Boston

Reflecting on a productive week at TIDES USA, where conversations with leaders across the peptide and oligonucleotide space reinforced the momentum behind this rapidly evolving field...

Sinopep Exhibits at The 21st Drug Discovery Strategic Summit (DDSS)

The 21st Drug Discovery Strategic Summit (DDSS) has wrapped, and we're still energized by the conversations and connections made at this year's event...

In-House Biocatalytic Synthesis of Non-Canonical Amino Acids for Peptide Therapeutics

Non-canonical amino acids present a fundamentally different supply challenge compared to proteinogenic residues. Standard amino acid suppliers operate at high volume for commodity materials; NCAA...

Sinopep’s New Formulation Facility

Since its founding in 2004, Sinopep has developed a robust and scalable formulation platform focused on delivering high-quality pharmaceutical products and CDMO solutions. Our recently expanded...

Sinopep Oligonucleotide GMP Manufacturing

Our new GMP oligonucleotide facility represents a major expansion in our ability to manufacture oligonucleotide API and NCE therapeutics, including antisense oligonucleotides (ASOs) and siRNA, at...