Small Molecule APIs
Small Molecules
Small Molecule API Services
Over half of all marketed drugs are chiral, with most utilizing a single, therapeutically active enantiomer. At Sinopep, our scientists have spent over two decades mastering the large-scale, stereoselective synthesis of complex intermediates and APIs with multiple chiral centers. Our Asymmetric Synthesis Platform offers a comprehensive, one-stop solution for integrating chirality through biocatalysis, asymmetric hydrogenation and reductions, enantioselective coupling reactions, and chiral auxiliary-assisted methodologies.
To further enhance efficiency and safety, our Continuous Flow Chemistry Platform provides a compact, scalable, and economically viable alternative to traditional batch processing—especially when handling energetic reagents, unstable intermediates, or temperature-sensitive reactions. We support projects from pre-clinical to commercial scale, including non-GMP and GMP production. A key capability is continuous photochemistry, where precisely tuned light sources (UV to visible) drive complex transformations—such as pericyclic and single-electron transfer reactions—that are often difficult to achieve in batch reactors.
Small Molecule API Pipeline
- Agomelatine
- Atorvastatin Calcium
- Epalrestat
- Fulvestrant
- Oseltamivir Phosphate
- Sodium Picosulfate
- Alogliptin Benzoate*
- Roxadustat*
- Sulindac
- Ezetimibe
- Risdiplam*
- Baloxavir marboxil*
- Elacestrant dihydrochloride*
- Dydrogesterone
- Elacestrant*
- Orforglipron*
- Rimegepant*
- Ubrogepant*

