Service Request

Quotation Request for Manufacturing Services

We specialize in manufacturing of peptide & Oligo NCEs for early- and late-phase programs, and commercial-scale production.

GMP Manufacturing Capacity

GMP Peptides

Clinical-Grade Peptide Manufacturing Services

Oligo Manufacturing Service Request

Oligonucleotides

Research- and Clinical-Grade Manufacturing Services

Research Grade Peptide Synthesis

Custom Peptides

Research-Grade Custom Peptide Synthesis Services

FTE Lab worker

FTE

Full-Time Equivalent Discovery Services

Full-Service Peptide & Oligo CDMO

At Sinopep, we provide a streamlined way for researchers and developers to request custom synthesis quotes across three specialized service areas: Peptide, Oligonucleotide, and GMP Peptide manufacturing. Whether you need research-grade materials for discovery, complex oligos with advanced modifications, or phase-appropriate GMP peptide production for clinical and commercial programs, our integrated platform makes it easy to begin your project.

Service Comparison

The table compares Discovery Peptides’ service levels, from standard research-grade peptide synthesis with basic characterization, to advanced GMP manufacturing with full regulatory support, specialized oligonucleotide synthesis (including ASOs, siRNA, modified backbones, and conjugates), and a dedicated Full-Time Equivalent (FTE) team model for long-term projects. It clearly shows how offerings progress from essential analytical and technical services to comprehensive clinical-grade production and scalable, continuous collaboration options.

Discovery Peptides GMP Manufacturing Oligonucleotides Full-Time Equivalent (FTE)
Standard Services: Standard Services: Service Types: Our FTE Model:
✓ HPLC & MS Characterization ✓ GMP Peptide Technical Package ✓ Antisense Oligos (ASOs), siRNA, miRNA ✓ Continuous Operations
✓ Expert Technical Support ✓ Regulatory Support ✓ Morpholino Phosphorodiamidate Oligomers (PMOs) ✓ Dedicated Team Allocation
Available Services: ✓ Phase-Appropriate Controls ✓ Aptamers, CpG oligos, Decoys ✓ Budget Certainty
✓ Conjugation Services ✓ CMC Documentation for IND/NDA ✓ Peptide-Oligo Conjugates (POCs) and PPMOs ✓ Full Data Visibility
✓ Aliquoting Services ✓ DMF Compilation & Submission ✓ Backbone: PO, PS, PN ✓ Administrative Efficiency
✓ Amino Acid Analysis ✓ Annual Product Reviews ✓ Base: 2'-OMe, 2'-MOE, 2'-F, 2'-LNA, cEt ✓ Scalable Flexibility
✓ Solubility Testing ✓ Operational Continuity
✓ Endotoxin Testing
✓ Water Content Analysis

Recent Publications

All CategoriesCitationsInsights from SinopepPublicationsWhitepaper

Efficient Hybrid Synthesis of Amycretin

Multi-receptor agonist peptides represent one of the fastest-growing frontiers in metabolic disease therapeutics. Molecules such as amycretin, a dual GLP-1 and amylin receptor agonist, combine two...

API Substance Quality as a Determinant of Formulation Outcomes: A Review of Sodium Caprate-Enhanced Oral Semaglutide Tablet Development

Oral delivery of semaglutide is limited by low membrane permeability and gastrointestinal degradation, restricting unassisted bioavailability to well below one percent, a barrier Rybelsus® overcomes...

Reagent-Quenching for Reducing Solvent Consumption in Solid-Phase Peptide Synthesis

This paper describes a reagent-quenching strategy in which a Brønsted acid compound is introduced during the post-deprotection wash to chemically neutralize residual piperidine in situ, converting it...

In-House Biocatalytic Synthesis of Non-Canonical Amino Acids for Peptide Therapeutics

Non-canonical amino acids present a fundamentally different supply challenge compared to proteinogenic residues. Standard amino acid suppliers operate at high volume for commodity materials; NCAA...

Noncanonical Amino Acids in Oral Peptide Drug Design

Macrocyclic peptides achieve therapeutic efficacy through precisely engineered molecular architectures that simultaneously optimize target binding, metabolic stability, and membrane permeability. The...

Commercial-Scale Peptide Disulfide Cyclization at High Concentration

Conventional oxidation methods typically demand extreme dilution (<0.1–1 mg/mL) to favor intramolecular cyclization and suppress intermolecular side reactions. Sinopep has developed a methodology...

Improved Detection of Silver Ions to Support Environmental Sustainability

Li, S.; Jiao, J.; Meng, S.; Zhao, C.; Wu, J. Selective Ag⁺ Sensing and Cellular Imaging Based on Hydrophilic Modulated Peptide Probe. Luminescence 2026, 41, e70397...

Nanometer-Scale Water-Soluble Macrocycles from Nanometer-Sized Amino Acids

Gothard, Chris M., and James S. Nowick. The Journal of Organic Chemistry 75.6 (2009): 1822-1830...

Years Experience

Employees

Capacity (MT/yr)

GMP Faclities

Inspection History

Since 2014, Sinopep’s GMP manufacturing facilities have successfully passed four (4) inspections conducted by the U.S. FDA, demonstrating our strong commitment to global regulatory compliance and product quality. In addition to these FDA audits, Sinopep has also undergone inspections by the Korean MFDS and has successfully completed 20 regulatory audits conducted by the NMPA in China.